Trata-se do capítulo “Overdetermined Oedipus: Mommy, Daddy, and Me as Desiring-Machine” in: BUCHANAN, Ian. (Org). A Deleuzian Century?. Durham: Duke University Press, 1999. (N.T.).

Media representations are presently a determinant form in fixing and promoting memory in modern times. These representations are synthetic cultural formations, complex abstractions which function under pre-determined options. The search for and selection of objects and their images, usually fo..

Neste texto, discutimos disposições teórico-metodológicas do Grupo de Estudos sobre Numeramento (GEN), na busca de compreender os modos como pessoas, em suas singularidades, mas como sujeitos sociais, se apropriam de práticas matemáticas, tomadas como práticas discursivas. A pesquisa, a formação docente e a atuação do GEN em contextos educativos diversos inserem-se nos campos da Educação Matemática e do Letramento, pois buscam conhecer sujeitos da Educação (crianças, adolescentes, jovens, pessoas adultas e idosas), que, vivendo em sociedades ‘grafocêntricas’ e ‘quanticratas’, movidos por (...) intenções pragmáticas e parametrizados por referências culturais, forjam usos dos sistemas linguísticos relacionados à quantificação, mensuração, ordenação, classificação e organização de formas e espaços. A esses usos chamamos práticas de numeramento. As situações em que as identificamos – os eventos de numeramento –, em seu caráter histórico, são tomadas como unidades da análise das intenções dos usos, dos efeitos de sentido que logram produzir e, principalmente, de como sujeitos se constituem nas interações por eles mediadas, ao produzirem e tensionarem significados. Na seção ‘Compreendendo práticas matemáticas como práticas discursivas: foco, perspectiva e referenciais teórico-metodológicos do Grupo de Estudos sobre Numeramento (GEN)’: explicitamos o propósito do Programa de Pesquisa do Grupo (conhecer sujeitos e grupos sociais que protagonizam práticas de numeramento); justificamos sua base teórica (os Estudos do Letramento como Prática Social; a Pedagogia da Liberdade e da Autonomia; a compreensão da cognição como processo social; e a abordagem sociológica da Linguagem); assumimos a etnografia como lógica de investigação; e propomos a análise de interações como principal tratamento do material empírico. Apontamos também, dadas as especificidades dos sujeitos, a necessidade do diálogo com diversos campos: Educação de Pessoas Jovens, Adultas e Idosas (EJA), Sociologia da/s Infância/s; Estudos da/s Juventude/s; Educação do Campo; Educação Indígena; Educação de Pessoas Surdas; Formação Docente, entre outros. Na seção ‘Compreendendo práticas de numeramento como práticas de letramento: fertilidade analítica e pedagógica das escolhas teóricas’, esclarecemos como nossos estudos se inserem numa perspectiva Etnomatemática, porque contribuem para conhecermos os sujeitos que vemos protagonizar práticas matemáticas ao assumirem posições discursivas – portanto, sociais, culturais e políticas. Na seção ‘Compreendendo a aprendizagem matemática como apropriação de práticas de numeramento: desdobramentos da concepção de práticas matemáticas como práticas discursivas’, apresentamos como o conceito de apropriação de práticas de numeramento, de inspiração vigostskiana, usado para contemplar múltiplos sentidos das ações dos sujeitos em eventos de numeramento, disponibiliza uma ferramenta teórica para compreender a aprendizagem matemática não como experiência cognitiva individual, mas como ação social. Na seção ‘Interlocuções teóricas e disposições analíticas dos estudos mais recentes do GEN’, indicamos como uma análise tridimensional do discurso (do texto, da situação discursiva e da prática social), adotada para conhecer melhor os sujeitos e reconhecê-los como sujeitos sociais, tem-nos conduzido às considerações de Paulo Freire sobre sujeito de cultura, sujeito de conhecimento, sujeito dialógico e sujeito do processo, que compõem o sujeito histórico, protagonista de eventos de numeramento. Na ‘coda’ (‘Reiterando’), reafirmamos o foco de nossa linha de investigação no campo da Educação Matemática: pessoas constituindo-se como sujeitos sociais, enquanto se apropriam de práticas de numeramento. (shrink)

“There`s only beauty if there is an interlocutor. The beauty of the lagoon is always someone” (Mãe, 2017, p.40). Valter Hugo Mãe expresses our desire in the making of this paper to share our experience of meeting refugee children, as part of an ongoing research project dedicated to exploring the conditions in which they live in Baixada Fluminense, Rio de Janeiro, Brazil, and the influences they bring with them from their birth countries. In the process of conducting this research, we (...) were surprised by a group of children who belong to the Warao ethnic group, and who have been welcomed by the municipality of Nova Iguaçu, which is part of Baixada Fluminense. The Warao are indigenous peoples from the North of Venezuela and their name means “canoe,” given their close relationship with water. A group of displaced Warao children and their families arrived in Nova Iguaçu after having “camped” out in the surroundings of Novo Rio bus station for a few weeks, followed by a sojourn in a public shelter, where the differences between them and the existing members of the institution led to conflict. Through a religious institution’s initiative, the families then found shelter in a small farm in the city of Japeri. They stayed there for six months, but once again were threatened by the prospect of eviction, after which they were finally welcomed in the city of Nova Iguaçu. The families–five interconnected units–expressed the wish to remain together and a social service institution found them a closed school building, which was modified to accommodate the group. When the Covid pandemic struck, the research and study group GEPELID began following the daily routine of these children at the shelter school and at the Marambaia welfare center. In their meetings with the Warao, the researchers were struck by their references to the Buriti tree as the “tree of life,” and the depths of its implications for their identity. In exploring this concept, the research group’s experience of radical cultural difference revealed the extent to which research in the human sciences is always a meeting with the other, and the relation between researcher and subjects an occasion for dialogue. (shrink)

The organization of the Herodotian narrative is based overall in the characterization of the despotism, however this can only mean something in Herodotus‟ work if opposed to the Greek ways of political organization and mainly in relation to democracy. However, the fact that the barbarians‟ despotism takes higher evidence in the work is enough to make the theme of tyranny dominate over the poliada organization? Could not we assume that the distinction of tyranny would not be only one way to (...) show the Greeks their own particularity? In this case, the exotic one, marvelous and the admirable one would lie in the fact that the Greeks organized a completely singular way of political organization, stranger to all the other known peoples. (shrink)

In order to demonstrate the great importance of Philosophy in the elaboration of current scientific theories, a parallel was drawn between concepts of pre-Socratic Philosophy and current modern theories. Thus, throughout this essay, the convergences between some elaborations developed by philosophers and their reinterpretation from a scientific point of view, supported by the scientific method and the present technological apparatuses, were exposed. In this sense, having as its core the reflection about the atomic theory of Leucippus and Democritus, we investigate (...) the way in which atomism dialogues with the modern Atomic Theory to the Quantum Theory, through concepts of Kosmos and Cosmology. In a second moment, origin of life theories were revisited from the pre-Socratic concepts of Psykhe. Finally, Philosophy and Science are brought together as possible and complementary tools for the restoration of the amplification of thought and investigative processes. (shrink)

A partir da psicanálise existencial sartriana, descrita na obra Saint Genet: Ator e Mártir, analisaremos os caminhos tortuosos que a subjetividade percorre na tentativa de se plenificar como objeto. Nosso propósito é demonstrar que Genet buscou identificar-se com seu ego para se colocar como um objeto de desprezo para a sociedade, porém, sua busca fracassa, pois, segundo Sartre, o homem jamais será completamente objetividade alienada no mundo. Nesse intuito, descreveremos brevemente os principais momentos da vida de Genet. Em sua infância, (...) teve seu ego-visto (ser-para-outro) constituído pelo olhar de outrem; a partir de então, realizou diversos esforços para se identificar com essa imagem alienada, entretanto - enquanto liberdade -, permaneceu frente a todas as suas tentativas de fixar um ego maldito com o qual se identificasse; e, por fim, encontrou apenas a sua própria subjetividade, exercendo sua liberdade no ofício de escritor. Concluiremos, portanto, que a subjetividade permanece livre e responsável, mesmo frente à construção do seu ego. (shrink)

Una forma determinante en la actualidad de fijar y difundir la memoria ocurre a través de las representaciones mediáticas. Las representaciones son formaciones culturales sintéticas, abstracciones complejas que actúan bajo opciones determinadas. La recogida y selección de objetos y sus imágenes, habitualmente desechados a lo que se considera la memoria, establecen los mecanismos desde los cuales se elabora la concreción de las representaciones. Por detrás del lastre sobre el cual reposa lo efímero de aquellas producciones culturales abarcadas por el neologismo (...) cada día más reiterado de "mediáticas", pervive algo que les allana en un sustrato de larga duración común a varias épocas. El artículo reflexiona acerca de los presupuestos por los cuales las representaciones mediáticas obran por fijar la memoria y traerla a nuestra presencia bajo soportes tecnológicos.Media representations are presently a determinant form in fixing and promoting memory in modern times. These representations are synthetic cultural formations, complex abstractions which function under pre-determined options. The search for and selection of objects and their images, usually forgotten by memory, establish the mechanisms from which the fixation of representations is undertaken. Behind the garbage on which ephemeral aspects of cultural productions are undertaken by neologisms which are more reiterated in the media, something survives that places them in a long duration substratum common to many moments. This article reflects on the presuppositions under which media representations work to fix themselves in the memory and revive them in the present by use of technological support. (shrink)

BackgroundThis study analyzed the difference in psychological distress of the healthcare workers in three different periods of the coronavirus disease 2019 (COVID-19) pandemic in Argentina. Specifically, from the third week of the mandatory quarantine through the two following weeks.MethodsAnalysis of the responses of 1,458 members of the health personnel was done on a questionnaire on healthcare workers concerns regarding the care of patients with coronavirus, indicators of depression, anxiety, intolerance of uncertainty, and coping.ResultsThe psychological indicators that were considered presented differences (...) between the evaluated periods. Perceived concerns about the possibility of infecting loved ones and infecting themselves were greatest in the periods after the onset of the pandemic. In addition, the perception of how the work environment worsened and how lack of sleep interfered with their work was also higher in periods 2 and 3. The same results were found in the indicators of depression, anxiety, and intolerance of uncertainty. Finally, the indicators of high tension and concurrent lack of emotional control, which was greater in the last periods evaluated, were also expressed in the coping strategies (showing emotional lability, only contained by hypercontrol).ConclusionThe differences found in the psychological indicators between the evaluated periods support the need for early psychological care of health personnel which should be a priority of public health and a fundamental fact to increase its immediate effectiveness in the care of infected patients. (shrink)

Automated neuropsychiatric batteries have been used in research and clinical practice, including for chronic diseases, such as Systemic Lupus Erythematosus. The Pediatric Automated Neuropsychological Assessment Metrics battery, originally developed for use in American-English speaking individuals, allows tracking of cognitive functions. It can be applied to people over 9 years old. The aim of this study was to translate and present initial validation data from the Ped-ANAM into Brazilian-Portuguese. We translated the battery according to Beaton’s guidelines. Psychometric properties were tested, internal (...) consistency was analyzed by Cronbach’s alpha coefficient, test-retest reliability by the intraclass correlation coefficient. Further, we measured the test execution speed at both times as a temporal stability. Principal component analysis was used for structural validity. Evidence of construct validity was assessed through assessment of the relationships with the Wechsler Intelligence Scales. All participants prior to the start of study related activities signed an informed consent form approved by the local ethics committee. A sample of 230 individuals [mean of age: 23 years; 65% females] was included; a subset of 51 individuals [mean of age: 18 years, 59% female] completed the Ped-ANAM twice to assess test-retest reliability, and another subset of 54 individuals [mean of age: 20.4 years; 67% female] completed the Wechsler Intelligence Scales for Children and Adult for assessment of the Ped-ANAM’s construct validity. Our results suggest that the internal consistency of the Ped-ANAM and its subtest test-retest reliability were excellent. There was no clustering in the Principal Components Analysis, suggestive of non-grouping of the evaluated variables. Construct validity assessment to the Wechsler Scales showed expected ranges of low to strong correlations. We concluded that, based on the results of this study, a cross-culturally validated Brazilian-Portuguese version of the Ped-ANAM has been developed and it is a reliable tool for the screening cognitive function. (shrink)

BackgroundMoral distress is a phenomenon that can lead to an imbalance of the mind and body. There are many coping strategies to overcome the obstacles that lead the subject to this condition. Some coping strategies are capable of being achieved through the cultivation of moral resilience.AimThe aim is to identify the strategies of moral resilience in the nursing management of University Hospitals in Brazil.Research designThe research design is the qualitative study with discursive textual analysis.Participants and research context: 44 nurse managers (...) and nurses in leadership positions participated in a total of 30 University Hospitals in Brazil. Data were collected online, using a questionnaire with open questions.Ethical considerationsThe Ethics Committee approved the study. Participants received information about the research, agreed to respond to the questionnaire, and were guaranteed anonymity.FindingsPersonal adaptive strategies (intrapersonal and interpersonal) and organizational collaborative strategies (intrinsic and transformational management) emerged from this process. The intrapersonal strategies involved elements of rationality, flexibility, rebalancing practices, moral courage, and detachment. The interpersonal strategies addressed support networks, team involvement, and dialog. Organizational strategies dealt with actions which reorient ethical infrastructure, ethical education, and psychological protection, as well as fostering dialogical relationships, empowerment, and cooperation.ConclusionFrom the perspective of social historical construction, it is understood that developing personal and organizational strategies is essential to cultivating moral resilience. (shrink)

O presente texto discute, em âmbito teórico, a relação entre acontecimento e narrativa midiática. Através de Louis Quéré, situa-se o acontecimento na dialética da experiência, originária da interação entre sujeitos e acontecimentos. Pensa-se a narrativa como um lugar de manifestação e representação das culturas e das ações dos sujeitos sobre o mundo. Volta-se para a narrativa por meio da tríplice mimese de Paul Ricoeur. No âmbito analítico, o texto realiza incursões e interpretações acerca da derrota da seleção brasileira de futebol (...) para a seleção alemã por sete gols a um na semifinal da Copa do Mundo de Futebol de 2014 e busca compreender como as capas de alguns jornais brasileiros produzem uma ressignificação do revés do Brasil na Copa de 1950, conhecido como Maracanaço. (shrink)

Background:Moral distress is considered to be the negative feelings that arise when one knows the morally correct response to a situation but cannot act because of institutional or hierarchal constraints.Objectives:To analyze moral distress and its relation with sociodemographic and academic variables in undergraduate students from different universities in Brazil.Method:Quantitative study with a cross-sectional design. Data were collected through the Moral Distress Scale for Nursing Students, with 499 nursing students from three universities in the extreme south of Brazil answering the scale. (...) The data were analyzed in the statistical software SPSS version 22.0, through descriptive statistical analysis, association tests (t-test and analysis of variance), and linear regression models.Ethical considerations:Approval for the study was obtained from the Research Ethics Committee at Universidade Federal do Rio Grande.Findings:The mean intensity of moral distress in the constructs ranged from 1.60 to 2.55. As to the occurrence of situations leading to moral distress in the constructs, the frequencies ranged from 1.21 to 2.43. The intensity level of moral distress showed higher averages in the more advanced grades of the undergraduate nursing course, when compared to the early grades of this course (between 5 and 10 grade, average = 2.60–3.14, p = 0.000).Conclusion:The demographic and academic characteristics of the undergraduate nursing students who referred higher levels of moral distress were being enrolled in the final course semesters, were at a federal university, and had no prior degree as an auxiliary nurse/nursing technician. (shrink)

Since the onset of the COVID-19 pandemic, many parents have felt anxious, overwhelmed, and stressed out due to the changes in education and family and working routines. This work aimed to describe three dimensions of perceived parenting in the COVID-19 pandemic context, describe possible changes perceived by mothers in their children’s behavior during the social isolation phase, analyze if behavioral changes vary according to the dimension of perceived parenting, and analyze whether the characteristics of perceived parenting dimensions vary with mother’s (...) age, number of children and number of work hours. The purposive sample consisted of 646 mothers of school-aged children in Argentina. Questionnaires on sociodemographic and work-related data, and on children’s behavior were administered, as well as an instrument that assessed the three parenting dimensions. The sociodemographic and work-related variables of the study were described using descriptive statistics: measures of central tendency, frequencies, and percentages. The changes perceived in children’s behavior according to the reports given by the mothers regarding positive parenting, parenting stress, and school support were compared using the Mann Whitney’s U test, respecting the qualitative nature of the evaluated indicators. A factorial MANOVA was conducted to analyze the effect of mother’s age, ä number of children, and the number of work hours on parenting perceived by mothers. Parenting dimensions influenced the perceived children’s behavior. Mothers with higher positive parenting perceived more changes in their children’s behavior. In addition, those mothers who were more stressed out perceived more problems in almost all the measured behaviors than less stressed mothers. The mothers who reported to have provided more school support to their children perceived that they adapted better to online classes. Finally, mothers’ age and the number of children I parenting, particularly on parenting stress and school support, whereas work hours did not. A number of children affected stress and school support, and age only affected parenting stress. The only significant interaction regarding parenting was observed between the number of children and the number of work hours, which specifically affected parenting stress. Although social isolation due to COVID-19 affected children’s behavior, according to mothers, this might be partially linked to the number of children, mothers’ age, and the mothers’ parenting style. These initial findings may allow the identification of some protective factors and some risk factors of parenting in the Argentine context of a pandemic, and the design of preventive psychoeducational interventions to optimize the psychological wellbeing of families. (shrink)

The aim of this article is to investigate and discuss the notions of difference and representation in Emmanuel Levinas and Gilles Deleuze, articulating such notions through the example of a university extension project involving the formation of a musical ensemble composed of autistic children. Our research involved a review of four major philosophical works—Emmanuel Levinas’ Totality and Infinity; Among Us: Essays On Alterity; and “The Concept Of Difference In Bergson”; and Gilles Deleuze’s Difference and Repetition--in addition to secondary references. The (...) main articulations of the investigation carried out in the project consist of aspects such as: taking responsibility for the autistic child through cultivating asymmetrical relationships, a process that takes place through sensibility, below any representation; and not totalizing the alterity involved while maintaining, at the same time, its radical difference. In addition, there is an emphasis in the work on the difference of each child, beyond his or her diagnostic identity, understanding that all participants are undergoing unique processes of differentiation, and that some differences are not more privileged than others, in that that such hierarchies are determined by power relations. Another contribution of this research is the emphasis on the intensive affective flows of children, and the construction of relationships of mutual affection, which increases the circulation of vital energy in each one. Finally, the results of the project are offered as guidelines for clinical practice, and for the cultivation of a politics of difference, as an alternative to hegemonic practices in autism studies in contemporary times. (shrink)

Poverty observed from business in the academic field has evolved in some publications and is characterized as a multidimensional phenomenon, having several theoretical strands that add their attention to this problem. The objective of this study is to identify and cluster the variables of poverty in the business area through the network analysis. There were 1,745 keywords mentioned in 566 papers about the theme present in the Scopus database between 2000 and 2016. The results demonstrate a network with four clusters: (...) (a) Economy, government and people; (b) Community, institutions and market; (c) Business and environment; and (d) Social aspects and finance. From the network, it is possible to understand the most cited categories of variables (research methodology and business aspects), the most consolidated relations between categories of variables (poverty and economic aspects), the most studied area (Economy, government and people), and the gaps to be explored. (shrink)

O objetivo foi descrever a ocorrência da violência sofrida por profissionais de saúde na Urgência e Emergência de um hospital do norte do país. Identificar a violência no setor de urgência e emergência possibilita gerar informações sobre a realidade de hospitais, o que colabora em sanar tais problemas que ocorram nos mesmos. A metodologia foi de abordagem quantitativa, com a aplicação de questionário com questões sobre violência sofrida e praticada no trabalho e sobre dados das vítimas e dos agressores, junto (...) aos profissionais do centro de urgência e emergência do hospital pesquisado. Os resultados da pesquisa apontaram a conclusão de que o principal autor de violência laboral é o paciente de 31 a 40 anos e as maiores vítimas são as mulheres que trabalham no turno da noite, recebem entre R$ 1.000 e 2.999 e não contam com pós-graduação. Portanto, são necessárias estratégias saneadoras para o problema da violência entre profissionais de saúde. (shrink)

_Review of: Consani, Cristina Foroni; Klein, Joel T.; Nour Sckell, Soraya, _Cosmopolitanism: From the Kantian Legacy to Contemporary Approaches_, Berlin, Duncker & Humblot, 2021, pp. 327. ISBN 978-3-428-58460-4._.

Este texto realiza uma revisão de literatura em torno dos principais aspectos que envolvem a construção da cena dissensual em Jacques Rancière, evidenciando como a potência fabulativa da racionalidade ficcional produz momentos quaisquer que perturbam os encadeamentos consensuais de ações, gestos, existências e experiências. A partir da produção de intervalos e liminaridades, é possível reconfigurar temporalidades e espacialidades a fim de desestabilizar e desierarquizar as relações de dominação e propor outros imaginários. O momento qualquer suspende a ordem corriqueira do tempo, (...) redispõe o visível, as ações e as formas como as coisas e os seres aparecem, a maneira habitual de ocupar um espaço, a forma de identificar-se como indivíduo e de inscrever-se nas relações. Assim, a cena de dissenso, tomada como singularidade e como operação a partir da qual se pode produzir momentos de rêverie (devaneio fabulador) que fraturam imaginários consensuais, altera o modo como lemos, vemos e ouvimos o outro e o mundo a nosso redor. Argumentamos que a cena realiza uma desmontagem das explicações previsíveis, deslocando consensos e oferecendo um imaginário antihierárquico e no qual coexistem múltiplos tempos, espaços e existências. (shrink)

Evidence is accumulating that individual and environmental factors in childhood and adolescence should be considered when investigating adult health and aging-related processes. The data required for this is gathered by comprehensive long-term longitudinal studies. This article describes the protocol of the Zurich Longitudinal Studies, a set of three comprehensive cohort studies on child growth, health, and development that are currently expanding into adulthood. Between 1954 and 1961, 445 healthy infants were enrolled in the first ZLS cohort. Their physical, motor, cognitive, (...) and social development and their environment were assessed comprehensively across childhood, adolescence, and into young adulthood. In the 1970s, two further cohorts were added to the ZLS and assessed with largely matched study protocols: Between 1974 and 1979, the second ZLS cohort included 265 infants, and between 1970 and 2002, the third ZLS cohort included 327 children of participants of the first ZLS cohort. Since 2019, the participants of the three ZLS cohorts have been traced and invited to participate in a first wave of assessments in adulthood to investigate their current health and development. This article describes the ZLS study protocol and discusses opportunities, methodological and conceptual challenges, and limitations arising from a long-term longitudinal cohort recruited from a study about development in early life. In the future, the ZLS will provide data to investigate childhood antecedents of adult health outcomes and, ultimately, will help respond to the frequent call of scientists to shift the focus of aging research into the first decades of life and, thus, to take a lifespan perspective on aging. (shrink)

The Operation Lava Jato, initiated in 2014 by the Ministry of Finance and carried out by the Brazilian Government Agency for Law Enforcement and Prosecution of Crimes, brought to light the unethical practices of several national contractors, despite their declared commitment to social responsibility and ethical management—a corporate conduct epitomized in the popular saying: “Do what I say; don’t do what I do”. In this chapter, we analyze such disconnection between discourse and practice vis-a-vis the literature on leadership and business (...) ethics, Brazilian culture and historical analyses of the Brazilian contractors industry. We examine the official discourse of a Brazilian contractor, as observed in documents retrieved from websites and statements to the press, and its practices, as depicted in the media and documented in testimonies already conducted by the federal courts and attached to the original case-files. Specifically, we aim to contribute to the reflection on management and ethics in Brazil by identifying and discussing the factors that seem to have promoted such disconnection, including aspects of national culture and the institutional environment, together with organizational culture and leadership. (shrink)

This paper presents an intuitive explanation about why and how Rawlsian Theory of Justice (Rawls in A theory of justice, Harvard University Press, Harvard, 1971) provides the foundations to a solution for algorithmic bias. The contribution of the paper is to discuss and show why Rawlsian ideas in their original form (e.g. the veil of ignorance, original position, and allowing inequalities that serve the worst-off) are relevant to operationalize fairness for algorithmic decision making. The paper also explains how this leads (...) to a specific MinMaxfairness solution, which addresses the basic challenges of algorithmic justice. We combine substantive elements of Rawlsian perspective with an intuitive explanation in order to provide accessible and practical insights. The goal is to propose and motivate why and how the MinMaxfairness solution derived from Rawlsian principles overcomes some of the current challenges for algorithmic bias and highlight the benefits provided when compared to other approaches. The paper presents and discusses the solution by building a bridge between the qualitative theoretical aspects and the quantitative technical approach. (shrink)

Synaptophysin (Syp) was the first synaptic vesicle (SV) protein to be cloned. Since its discovery in 1985, it has been used by us and by many laboratories around the world as an invaluable marker to study the distribution of synapses in the brain and to uncover the basic features of the life cycle of SVs. Although single gene ablation of Syp does not lead to an overt phenotype, a large body of experimental data both in vitro and in vivo indicate (...) that Syp (alone or in association with homologous proteins) is involved in multiple, important aspects of SV exo‐endocytosis, including regulation of SNARE assembly into the fusion core complex, formation of the fusion pore initiating neurotransmitter release, activation of SV endocytosis and SV biogenesis. In this article, we summarise the main results of the studies on Syp carried out by our and other laboratories, and explain why we believe that Syp plays a major role in SV trafficking. BioEssays 26:445–453, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

This paper is the result of my participation in a discussion event of Problema. Anuario de filosofía y teoría del derecho entitled “The Construction of Precedent in Civil Law: Debates, Concepts and Challenges”. Several colleagues with a vast knowledge on the subject of judicial precedent participated in this seminar, which also delved into the widely debated aspects of judicial precedent focused on the case of Chile. The entire discussion aimed at proposing solutions, as well as shedding some light on some (...) of its important aspects.Starting from such transcendental concepts as, rationality and argumentative use, it is possible to find certain problems arising from the improper use of the above concepts, which in turn leads us to stare decisis, a term that if used incorrectly may result in an act against the internal independence of judges. (shrink)

The purpose of this scoping review is to investigate the value of creative arts therapies in healthy older adults. This article aims to shed light on current knowledge concerning the effectiveness of art therapies for the prevention of common age-related conditions using the definition of art therapy provided by the American Art Therapy Association, as well as Cohen’s conceptual framework for the psychological conceptualization of the relationship between the arts and health in later life. The objective is to carefully capture (...) subthreshold situations of distress, which are often not taken into account and primarily involve psychological aspects that are crucial in the multidimensional perspective of healthy aging. Twelve articles were selected and examined following an initial electronic search on 3 databases. A thematic analysis of the results identified four major themes: improving cognitive performance and proprioception; enhancing self-identity and meaningful life; reducing feelings of loneliness and depressive symptoms; and the importance of socialization. All these aspects constitute the basis for preventing psychological distress and enhancing mental well-being for healthy aging. (shrink)

El presente trabajo es el resultado de mi participación en el evento de discusión de la revista Problema. Anuario de Filosofía y Teoría del Derecho, que llevó por nombre “La construcción del precedente en el Civil Law: debates, conceptos y desafíos”, en el cual participaron varios colegas con un amplio conocimiento en el tema del precedente judicial; de igual forma, ahonda en los temas de mayor debate dentro de lo referente al precedente judicial, enfocado al caso chileno. Todo ello, con (...) la finalidad de proponer algunas soluciones al respecto, así como dilucidar ciertos aspectos importantes dentro del precedente. Partiendo de conceptos tan trascendentes como la prescriptibilidad, la racionalidad y el uso argumentativo, se logra llegar a ciertas problemáticas provocadas por el mal uso de los conceptos previamente mencionados, que a su vez nos conduce al stare decisis, término que mal utilizado puede resultar en un acto contrario a la independencia interna de la cual gozan los jueces. (shrink)

Platelets have important hemostatic functions in repairing blood vessels upon tissue injury. Cytokines, growth factors, and metabolites stored in platelet α‐granules and dense granules are released upon platelet activation and clotting. Emerging evidence indicates that such platelet‐derived signaling factors are instrumental in guiding tissue regeneration. Here, we discuss the important roles of platelet‐secreted signaling factors in skeletal muscle regeneration. Chemokines secreted by platelets in the early phase after injury are needed to recruit neutrophils to injured muscles, and impeding this early (...) step of muscle regeneration exacerbates inflammation at later stages, compromises neo‐angiogenesis and the growth of newly formed myofibers, and reduces post‐injury muscle force production. Platelets also contribute to the recruitment of pro‐regenerative stromal cells from the adipose tissue, and the platelet releasate may also regulate the metabolism and proliferation of muscle satellite cells, which sustain myogenesis. Therefore, harnessing the signaling functions of platelets and the platelet secretome may provide new avenues for promoting skeletal muscle regeneration in health and disease. (shrink)

Este artigo pretende analisar as interfaces da produção científica feminina no início do século XX com a constituição do espaço psi no Brasil, utilizando para tanto um artigo do periódico católico "A Ordem" e uma tese da Faculdade de Medicina do Rio de Janeiro. Para sermos mais precisos, nosso recor..

La nouvelle édition des Éléments de rythmanalyse et autres essais sur les temporalités, parue grâce à Claire Revol en 2019 chez Eterotopia, vient d'être traduite en portugais par Flávia Martins, professeur de géographie à l'UFF, et Michel Moreaux, docteur en géographie de l'UERJ. L'ouvrage est publié par l'éditeur Consequência. Cette préface est une invitation à la lecture des Éléments de rythmanalyse : introduction à la connaissance des rythmes, d'Henri Lefebvre. Nous souhaitons que cette œuvre aux multiples - Sociologie – (...) Nouvel article. (shrink)

This book articulates a participatory conception of deliberative democracy that takes the democratic ideal of self-government seriously. It aims to improve citizens' democratic control and vindicate the value of citizens' participation against conceptions that threaten to undermine it. The book critically analyzes deep pluralist, epistocratic, and lottocratic conceptions of democracy. Their defenders propose various institutional ''shortcuts'' to help solve problems of democratic governance such as overcoming disagreements, citizens' political ignorance, or poor-quality deliberation. However, all these shortcut proposals require citizens to (...) blindly defer to actors over whose decisions they cannot exercise control. Implementing such proposals would therefore undermine democracy. Moreover, it seems naive to assume that a community can reach better outcomes 'faster' if it bypasses the beliefs and attitudes of its citizens. Unfortunately, there are no 'shortcuts' to make a community better than its members. The only road to better outcomes is the long, participatory road that is taken when citizens forge a collective will by changing one another's hearts and minds. However difficult the process of justifying political decisions to one another may be, skipping it cannot get us any closer to the democratic ideal. Starting from this conviction, the book defends a conception of democracy ''without shortcuts''. This conception sheds new light on long-standing debates about the proper scope of public reason, the role of religion in politics, and the democratic legitimacy of judicial review. It also proposes new ways to unleash the democratic potential of institutional innovations such as deliberative minipublics. (shrink)